ACTIVE SURVEILLANCE IS NEEDED FOR AMP-C β-LACTAMASE AND ESBL-PRODUCING ORGANISMS IN CHILDREN
ESPID Education. KHARE M. Jun 7, 2011; 7678 Disclosure(s): none to disclose
Dr. MILIND KHARE
Dr. MILIND KHARE

This content is available to ESPID members only


Click here for more information or if you are considering becoming an ESPID member.

Abstract
Discussion Forum (0)
Rate & Comment (0)
ACTIVE SURVEILLANCE IS NEEDED FOR AMP-C β-LACTAMASE AND ESBL-PRODUCING ORGANISMS IN CHILDREN

Background and aims:
The emergence of multi-resistant Amp-C & ESBL-producing gram-negative bacteria in the community is one of the most significant recent epidemiologic changes in infectious diseases. In the years 2007-8 laboratory had vitek1 machine which could identify extended-spectrum β-lactamases (ESBLs) from isolates which were cefpodoxime (used as a marker) resistant. In an audit done from January 2007 to June 2008, 17 ESBLs were isolated from children. A method which can identify Amp-C β-lactamase and ESBL producing bacteria was adopted and evaluated for active surveillance.

Methods
Laboratory in the hospital adopted the five disc diffusion method on a single plate in the last quarter of 2008. Evaluation was done over a period of from 1st July 2009 to 31st December 2010.Type of specimen, location where specimen was collected; age of the patient was recorded

Results
72 children were identified with Amp C producers and 33 with ESBLs aged 2days to 16 years. 53(74%) Amp-C isolates & 31(94%) ESBLs were obtained from urine, while the others from a cough swab, pus, eye, ears and umbilicus (no bacteraemia). 57(79%) Amp-C isolates & 29(88%) ESBLs were obtained from the community specimens.

Conclusions
Thus Amp-C & ESBL-producing organisms are reported with increasing incidence in the children and the number increased manifold with active surveillance which was sought as they are potentially serious pathogens. It is important to look for these multi-resistant infections so as maintain high standard of quality of children care and best management of children’s illness episodes in the hospitals & community.

Code of conduct/disclaimer available in General Terms & Conditions
Anonymous User Privacy Preferences

Strictly Necessary Cookies (Always Active)

MULTILEARNING platforms and tools hereinafter referred as “MLG SOFTWARE” are provided to you as pure educational platforms/services requiring cookies to operate. In the case of the MLG SOFTWARE, cookies are essential for the Platform to function properly for the provision of education. If these cookies are disabled, a large subset of the functionality provided by the Platform will either be unavailable or cease to work as expected. The MLG SOFTWARE do not capture non-essential activities such as menu items and listings you click on or pages viewed.


Performance Cookies

Performance cookies are used to analyse how visitors use a website in order to provide a better user experience.



Google Analytics is used for user behavior tracking/reporting. Google Analytics works in parallel and independently from MLG’s features. Google Analytics relies on cookies and these cookies can be used by Google to track users across different platforms/services.


Save Settings