ESPID Education. Shai S. Jun 7, 2011; 7700 Disclosure(s): The ESPED fees were covered by GlaxoSmithKline
Sonu Shai
Sonu Shai

This content is available to ESPID members only

Click here for more information or if you are considering becoming an ESPID member.

Discussion Forum (0)
Rate & Comment (0)
According to the German Infection Protection Act, all cases of rotavirus (RV) diseas in Germany are to be reported to the authorities. There are no data concerning the severity of the disease. Aim of study was to prospectively determine the incidence and the outcome in ver severe cases of RV disease.

Cases of very severe RV diesease were queried through the collection unit for rare paediatric diseases in Germany (ESPED) using anonymous questionnaires. Data acquisition begean in April 2009 for a planned period of two years.
Inclusion criteria were detection of RV in faeces, patient age 0 - 16 years and one or more of the following criteria: intensive care treatment, hyper- or hyponatremia (>155 mmol/ or <125 mmol/l), clinical signs of encephalopathy (somnolence, seizures, apnoas), deathe due to complications related to RV disease.

96 cases were reported, 96 are evaluable. 17/96 cases were nosocomially acquired, 13/17 were in neonatal intensive care.

79/96 cases were community acquired, their mean age was 16,5 months (0 - 168 months), mean
hospital stay was 10 days (1 - 85 days). 46/79 patients needed intensive care treatment, 55/96
children had signs of encephalopathy, 33/79 cases had a hyper- or hyponatremia. Two death
were reported (a child with syndromal disease with multiple organ anomalies and a child due to hypovolemic shock).

This study shows that RV infections may take a life-threatening course. A substantial number of these cases were nosocomially acquired.
Code of conduct/disclaimer available in General Terms & Conditions
Anonymous User Privacy Preferences

Strictly Necessary Cookies (Always Active)

MULTILEARNING platforms and tools hereinafter referred as “MLG SOFTWARE” are provided to you as pure educational platforms/services requiring cookies to operate. In the case of the MLG SOFTWARE, cookies are essential for the Platform to function properly for the provision of education. If these cookies are disabled, a large subset of the functionality provided by the Platform will either be unavailable or cease to work as expected. The MLG SOFTWARE do not capture non-essential activities such as menu items and listings you click on or pages viewed.

Performance Cookies

Performance cookies are used to analyse how visitors use a website in order to provide a better user experience.

Google Analytics is used for user behavior tracking/reporting. Google Analytics works in parallel and independently from MLG’s features. Google Analytics relies on cookies and these cookies can be used by Google to track users across different platforms/services.

Save Settings